Every time a drug company press release of vaccine trial results blasts through the media, it’s followed by criticism of “science by…
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Bias Radical Vaccine Trial Transparency & Press Release Readouts: What’s the Problem?
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Bias Clinical Trials Are Vital for the Rest Of Us. Are They a Good Deal for the Participants?
“People on a trial tend to do better”. Ordinarily, when I see someone make that point, I agree. But last week, when…
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Covid-19 The First Phase 3 Safety Picture & the Rise of Emergency Use: Covid-19 Vaccine Race, Month 10
NOTE: A lot has happened in the couple of weeks since I last updated this post. New monthly roundup coming soon! We’re…
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Covid-19 Meet the Women Leading Vanguard Covid-19 Vaccine Trials: A Sign of Progress & Reminder of What’s At Risk
Good news and inspirational women are coming in this post, I promise! But first, there’s a bunch of grim reading. Back in…
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Covid-19 Phase 3 Results in Sight for Some, While One Vaccine is Put on Hold: Covid-19 Vaccine Race, Month 9
We’re now into the ninth month since sequencing of the genome of SARS-Cov-2, the virus that causes Covid-19. And this is the…
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Covid-19 The FDA’s Epic Statistical Fail & Worse: Has Informed Consent Been Made Next To Impossible?
Enthusiasm for an experimental intervention often gets the better of doctors’ critical thinking. I think that happened with the advocates for Covid-19…
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Covid-19 Vaccine Contrasts & Massive Volunteer Mobilization: Covid-19 Vaccine Race, Month 8
We’re now into the eighth month since sequencing of the genome of SARS-Cov-2, the virus that causes Covid-19. And this is the…
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Covid-19 The Clinical Trial Results Stampede Begins: Covid-19 Vaccine Race, Month 7
We’re now into the seventh month since sequencing of the genome of SARS-Cov-2, the virus that causes Covid-19. This is the second…
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Covid-19 Study Publications Must Be Up-To-Date in Covid Time & That New Hydroxychloroquine Study
When I woke up yesterday morning, I saw that hydroxychloroquine had become a trending topic on Twitter again overnight. And – good…
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Covid-19 Covid-19 Vaccine Race, Month 6: First Emergency Use & Phase 3 Trials
We’re now into the sixth month since the genome of the new coronavirus was sequenced. Twelve to 18 months is the soonest…
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Evidence Science Heroes and Disillusion
“Never have heroes” – I’ve heard some version of that a lot in the last couple of months, from people disillusioned by…
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Bias Let’s Be Serious About Bias in Protocols of Systematic Reviews
A detailed pre-specified protocol is supposed to be the superpower of a systematic review: its contents literally put the “systematic” into review…