We’re now into the sixth month since the genome of the new coronavirus was sequenced. Twelve to 18 months is the soonest…
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Covid-19 Covid-19 Vaccine Race, Month 6: First Emergency Use & Phase 3 Trials
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Evidence Science Heroes and Disillusion
“Never have heroes” – I’ve heard some version of that a lot in the last couple of months, from people disillusioned by…
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Bias Let’s Be Serious About Bias in Protocols of Systematic Reviews
A detailed pre-specified protocol is supposed to be the superpower of a systematic review: its contents literally put the “systematic” into review…
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Covid-19 Reasons to Worry Less About the Explosion of Preprints
It looks as though preprints are here to stay in biomedicine, and I think that’s great. But I’ve been hearing variants of…
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Bias A Cartoon Guide to Conflict of Interest Claims, Fair & Foul
Claims of conflicts of interest have been one of the – let’s call it interesting – parts of being in debates…
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Covid-19 The Limits of Those Reviews of Masks For All and What We Do Know
Have you noticed that you see so many pictures of people wearing face masks during the 1918-20 influenza pandemic, but you don’t…
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Covid-19 First in Human: Covid-19 Vaccines & Tales of Phase 1 Clinical Trials Past
The people who sign up for the first-in-human trials of Covid-19 vaccines are about to do our societies an extraordinary service. Most…
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Evidence Why Do Scientists “Cite” the Top 5 Regrets of the Dying?
It pops up in my Twitter feed quite often, it seems to me. A scientist will buttress their argument that academics…
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Black History Month Black History Month: Chemists’ Powerful Stories & the Sociologist Who Studied Them
It was “a large, plain white building”, W.E.B. Du Bois wrote, “on the banks of the Seine, opposite the Rue des…
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Evidence The High Risk Methods of a New Systematic Review of HPV Vaccines
Back in 2018, the authors of a then-unpublished systematic review fired a spin- and error-laced salvo at the Cochrane review of…
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Annual open access roundup Open Access 2019: A Year of Momentum on the Subscription Off-Ramp
Plan S, the open access strategy from European funders in cOAlition S, gained momentum in 2019. However it pushed…
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Bias The Renewed Debate About Blinding in Clinical Trials
Things can go really off the rails in clinical trials. Take the most influential trial of the Mediterranean diet…