Mucosal vaccines go directly into the mucosal tissue where infection begins – for example, intranasally or via tablets. If they could induce…
-
Covid-19 A Huge Boost for Mucosal Covid Vax Development (Next Generation Update 15)
-
Bias Study Preregistration and Avoiding the Methods Fetish/Demonization Trap
This month, there was a thought-provoking 2-day workshop about preregistering studies, held at the Royal Society in London. The theme was “promises…
-
Covid-19 Picking Up Steam: Next Generation Covid Vaccine Update 14
The race for next generation vaccines is steadily heating up now. And this month, we’ve passed a major milestone: The first data…
-
Black History Month Black History Month: Early Mental Health Pioneers
There’s a chronology of “psychology’s contributions to the belief in racial hierarchy and perpetuation of inequality for people of color in U.S.&rdquo…
-
Evidence 5 Tips For Understanding Network Meta-Analysis
Network meta-analysis (NMA) is an extension of meta-analysis, combining trial evidence for more than 2 treatments or other interventions. This type of…
-
Covid-19 A Major First Next Generation Covid Vaccine: Could There Be More in 2024? (Update 13)
A next generation vaccine has been authorized by a major drug regulator for the first time. It’s based on a next generation…
-
Listicles 5 Things We Learned About Peer Review in 2023
This is my fifth annual research roundup about journal peer review. And we’re only averaging about one randomized trial a year. This…
-
Bias Unpacking the Biggest Trial Yet of Naming Authors in Peer Review
This is a very important trial. I had been looking forward to its results since it started a few years ago. It’s…
-
History The Weird Disconnect in a Debate About Whether Public Health is “Becoming” Illiberal
“Is public health becoming illiberal?,” asked Katelyn Jetelina last week. I assumed it would be a classic case of Betteridge’s Law &ndash…
-
Covid-19 Advancing Past Early Trials – Plus Shooting for Lifelong Immunity (Next Generation Covid Vax Update 12)
A massive funding boost from Project NextGen enables 3 phase 2b trials of next generation Covid vaccines to start in the US…
-
Evidence From the Lab to Evidence Reviews to Communication (Sicily Conference Part 3)
The Sicily Evidence-Based Healthcare Conference was a treat, and not just because of the glorious location and hospitality. It was big enough…
-
Evidence Is Critical Appraisal Training for Clinicians Doomed? (Sicily Conference Part 2)
The first shot against critical appraisal training for clinicians came quickly – in the opening lecture, in fact. And it seemed to…