“People on a trial tend to do better”. Ordinarily, when I see someone make that point, I agree. But last week, when…
-
Bias Clinical Trials Are Vital for the Rest Of Us. Are They a Good Deal for the Participants?Read more
-
Covid-19 The First Phase 3 Safety Picture & the Rise of Emergency Use: Covid-19 Vaccine Race, Month 10Read more
NOTE: A lot has happened in the couple of weeks since I last updated this post. New monthly roundup coming soon! We’re…
-
Covid-19 Meet the Women Leading Vanguard Covid-19 Vaccine Trials: A Sign of Progress & Reminder of What’s At RiskRead more
Good news and inspirational women are coming in this post, I promise! But first, there’s a bunch of grim reading. Back in…
-
Covid-19 Phase 3 Results in Sight for Some, While One Vaccine is Put on Hold: Covid-19 Vaccine Race, Month 9Read more
We’re now into the ninth month since sequencing of the genome of SARS-Cov-2, the virus that causes Covid-19. And this is the…
-
Covid-19 The FDA’s Epic Statistical Fail & Worse: Has Informed Consent Been Made Next To Impossible?Read more
Enthusiasm for an experimental intervention often gets the better of doctors’ critical thinking. I think that happened with the advocates for Covid-19…
-
Covid-19 Vaccine Contrasts & Massive Volunteer Mobilization: Covid-19 Vaccine Race, Month 8Read more
We’re now into the eighth month since sequencing of the genome of SARS-Cov-2, the virus that causes Covid-19. And this is the…
-
Covid-19 The Clinical Trial Results Stampede Begins: Covid-19 Vaccine Race, Month 7Read more
We’re now into the seventh month since sequencing of the genome of SARS-Cov-2, the virus that causes Covid-19. This is the second…
-
Covid-19 Study Publications Must Be Up-To-Date in Covid Time & That New Hydroxychloroquine StudyRead more
When I woke up yesterday morning, I saw that hydroxychloroquine had become a trending topic on Twitter again overnight. And – good…
-
Covid-19 Covid-19 Vaccine Race, Month 6: First Emergency Use & Phase 3 TrialsRead more
We’re now into the sixth month since the genome of the new coronavirus was sequenced. Twelve to 18 months is the soonest…
-
Evidence Science Heroes and DisillusionRead more
“Never have heroes” – I’ve heard some version of that a lot in the last couple of months, from people disillusioned by…
-
Bias Let’s Be Serious About Bias in Protocols of Systematic ReviewsRead more
A detailed pre-specified protocol is supposed to be the superpower of a systematic review: its contents literally put the “systematic” into review…
-
Covid-19 Reasons to Worry Less About the Explosion of PreprintsRead more
It looks as though preprints are here to stay in biomedicine, and I think that’s great. But I’ve been hearing variants of…