Things can go really off the rails in clinical trials. Take the most influential trial of the Mediterranean diet…
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Bias The Renewed Debate About Blinding in Clinical TrialsRead more
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Evidence It’s a Start: The Amended Version of the Cochrane Review on Exercise and CFSRead more
It’s tough, watching this play out slowly, step by painful step. As I’ve blogged before, ME/CFS consumer advocates have been…
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Evidence Am I Going to Need a Smaller Plate? In Which I Juggle a New Weight Loss Trial & Old Systematic ReviewsRead more
It just seems logical, doesn’t it? Super-sizing your food can super-size you. So when I used to see claims that…
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Bias Should We Trust Meta-Analyses with Meta-Conflicts of Interest?Read more
There are a couple of angles to look at researcher conflict of interest from. One is that a conflict could distort…
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Bias A Classic Case of Science “He Said”, “She Said”: How Psychologists Trying to Prevent PTSD Got ControversialRead more
Natural disasters have a lot in common with other major traumas, like life-threatening accidents and mass shootings – especially the emotional distress…
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Evidence Consumer-Contested Evidence: Why the ME/CFS Exercise Dispute Matters So MuchRead more
Sometimes, a dispute with a consumer movement comes along that has profound implications for far more than the people in it. I…
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Evidence Correcting the Record On That Critique of the Cochrane HPV Vaccine ReviewRead more
It can be a long, unrewarding slog to unpack the problems in a published paper. David Allison and colleagues talked…
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Bias Scientific Advocacy and Biases of the Ideological and Industry KindsRead more
I think the main thing I learned – very painfully – in 20 years as a health consumer advocate, is…
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Bias Boilover: The Cochrane HPV Vaccine Fire Isn’t Really About the Evidence – but it’s Critical to ScienceRead more
It was always a volatile situation. If it blew, it was going to be even harder to keep perspective through all the…
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Health The HPV Vaccine Should Be Preventing Cervical Cancer: Can We Tell Whether It Actually Is?Read more
The suspense is tough. Will the HPV vaccine reduce cervical cancer and related deaths or won’t it? It should, but this is…
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Evidence The HPV Vaccine: A Critique of a Critique of a Meta-AnalysisRead more
Battles over vaccine evidence sure can get toxic, can’t they? If you’re a diehard partisan, though, you can look for…
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Bias Systematic Reviews & Meta-Analyses: A 5-Step CheckupRead more
It’s easy to be a little blinded by the specialized statistical techniques in systematic reviews and meta-analyses. As with any type…